HLA antigen studies in a family with C2 deficiency.

Journal of immunogenetics ·Vol. 3 ·No. 5 ·1976-10-00 ·Pages 303-6

Opelz G, Glovsky MM

Abstract

Two children in a family were found to be homozygous for C2 deficiency; both parents and a third child were heterozygous. C2 deficiency was associated with the HLA haplotypes carrying the antigens B18 and DW2. Antigen A10 was absent in this family. Mixed lymphocyte culture studies among the family members confirmed the association of C2 deficiency with the HLA-D locus.

MeSH Terms

Adult Child Complement C2/deficiency Complement System Proteins/deficiency Female Genes Genetic Linkage HLA Antigens Heterozygote Histocompatibility Antigens Homozygote Humans Infant Lymphocyte Culture Test, Mixed Male Phenotype

Chemicals

Complement C2 HLA Antigens Histocompatibility Antigens Complement System Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Opelz G

Glovsky M M

Article Info

Journal

Journal of immunogenetics

Abbr.

J Immunogenet

ISSN

0305-1811

DOI

10.1111/j.1744-313x.1976.tb00588.x

Published

1976-10-00

Pages

303-6

Language

English

Region

England

NLM ID

0425125

Subset

External Links

PubMed source DOI: 10.1111/j.1744-313x.1976.tb00588.x

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