Phagocytized platelets: a source of lipids in human thrombi and atherosclerotic plaques.

Science (New York, N.Y.) ·Vol. 134 ·No. 3483 ·1961-09-29 ·Pages 946-7

CHANDLER AB, HAND RA

Abstract

Phagocytosis of lipid-rich platelets by monocytes and the transformation of such cells into lipophages containing fat was observed in human thrombi. The lipophages are similar to lipophages in atherosclerotic plaques. This observation supports the idea that some atherosclerotic plaques are organized mural thrombi.

Keywords

ARTERIOSCLEROSIS/blood BLOOD PLATELETS LIPIDS/blood PHAGOCYTOSIS THROMBOSIS/blood

MeSH Terms

Arteriosclerosis/blood Blood Platelets Humans Lipids/blood Macrophages Monocytes Phagocytosis Plaque, Atherosclerotic Thrombosis/blood

Chemicals

Lipids

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

CHANDLER A B

HAND R A

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.134.3483.946

Published

1961-09-29

Pages

946-7

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.134.3483.946 View journal details

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Phagocytized platelets: a source of lipids in human thrombi and atherosclerotic plaques.

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