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PMID: 13688945 Published · ppublish English Journal Article

Alteration of mutation frequency by treatment with actinomycin D.

Science (New York, N.Y.) ·Vol. 133 ·No. 3445 ·1961-01-06 ·Pages 40

BURDETTE WJ

Abstract

The frequency of lethal mutations occurring in Drosophila melanogaster was reduced by approximately one-half when irradiated males were treated with actinomycin D, which also inhibited the appearance of melanotic atypical growths in the strain used for the study.

Keywords
ACTINOMYCIN/pharmacology GENETICS/radiation effects RADIATION EFFECTS/experimental
MeSH Terms
Animals Dactinomycin/pharmacology Drosophila melanogaster Genetics/radiation effects Male Mutation Mutation Rate Radiation Effects
Chemicals
Dactinomycin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
BURDETTE W J
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.133.3445.40
Published
1961-01-06
Pages
40
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.133.3445.40 View journal details
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