Pyrimidine metabolism in man. I. The biosynthesis of orotic acid.

The Journal of clinical investigation ·Vol. 38 ·No. 5 ·1959-05-00 ·Pages 798-809

SMITH LH, BAKER FA

Abstract

暂无摘要

Keywords

OROTIC ACID/metabolism

MeSH Terms

Orotic Acid/metabolism

Chemicals

Orotic Acid

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

SMITH L H

BAKER F A

References (19)

19 references, click to expand

Studies of the biosynthesis of orotic acid.
J Biol Chem. 1956 Nov;223(1):195-205 PMID: 13376588
Enzymic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydro-orotic dehydrogenase.
Biochim Biophys Acta. 1953 Sep-Oct;12(1-2):223-34 PMID: 13115431
Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydroortic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin.
J Biol Chem. 1954 Apr;207(2):911-24 PMID: 13163076
Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. III. Ureidosuccinase.
J Biol Chem. 1955 Feb;212(2):909-20 PMID: 14353892
Enzymes of uracil metabolism in the Ehrlich ascites tumour and mammalian liver.
Biochim Biophys Acta. 1958 May;28(2):376-85 PMID: 13535735
Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism.
J Biol Chem. 1956 Aug;221(2):757-70 PMID: 13357469
Chromatography of the N-carbamoyl-amino acids (hydantoic acids).
Biochim Biophys Acta. 1954 Apr;13(4):560-3 PMID: 13159995
Studies on the mechanism of carbamylaspartic acid synthesis.
J Biol Chem. 1955 Apr;213(2):689-96 PMID: 14367329
Studies on the fibrinogen, dextran and phytohemagglutinin methods of isolating leukocytes.
Blood. 1956 May;11(5):436-54 PMID: 13315506
Carbamyl phosphate synthetase: studies on the mechanism of action.
J Biol Chem. 1958 Dec;233(6):1560-4 PMID: 13610873
The metabolism of orotic acid in aerobic bacteria.
J Bacteriol. 1955 Mar;69(3):250-5 PMID: 14367267
Purification and properties of dihydro-orotic dehydrogenase.
J Biol Chem. 1958 Dec;233(6):1398-406 PMID: 13610849
Studies on the biosynthesis of bacterial and viral pyrimidines. II. Dihydrouracil and dihydrothymine nucleosides.
J Biol Chem. 1957 Mar;225(1):397-407 PMID: 13416248
Studies of some precursors of pyrimidines.
J Biol Chem. 1955 Sep;216(1):37-49 PMID: 13252005
The stereospecific hydrogen exchange in the dihydroorotic dehydrogenase reaction.
J Biol Chem. 1957 May;226(1):307-16 PMID: 13428764
Colorimetric determination of carbamylamino acids and related compounds.
J Biol Chem. 1954 Jul;209(1):145-50 PMID: 13192067
Galactosemia, a congenital defect in a nucleotide transferase.
Biochim Biophys Acta. 1956 Apr;20(1):262-8 PMID: 13315373
The purification and properties of hydropyrimidine hydrase.
J Biol Chem. 1957 May;226(1):277-88 PMID: 13428761
Pyrimidine biosynthesis in Escherichia coli.
J Biol Chem. 1956 Aug;221(2):743-56 PMID: 13357468

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103862

Published

1959-05-00

Pages

798-809

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC293226

Subset

External Links

PubMed source DOI: 10.1172/JCI103862 PMC Full Text View journal details

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Pyrimidine metabolism in man. I. The biosynthesis of orotic acid.

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