The extraction of human urinary kinin (substance Z) and its relation to the plasma kinins.

British journal of pharmacology and chemotherapy ·Vol. 14 ·No. 1 ·1959-03-00 ·Pages 117-24

GADDUM JH, HORTON EW

Abstract

Human urinary kinin (substance Z) has been extracted by modifications of the methods previously described by Gomes (1955) and Jensen (1958). The separation of two oxytocic fractions from such extracts by paper pulp chromatography (Walaszek, 1957; Jensen, 1958) could not be confirmed. Substance Z could not be distinguished from kallidin, bradykinin or glass-activated kinin by parallel quantitative assays, thus confirming that these four substances are very closely related.

Keywords

KALLIKREIN URINE

MeSH Terms

Biological Assay Bradykinin Humans Immunologic Factors Kallidin Kallikreins Kinins Urinary Tract Urine

Chemicals

Immunologic Factors Kinins Kallidin Kallikreins Bradykinin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

GADDUM J H

HORTON E W

References (12)

12 references, click to expand

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Article Info

Journal

British journal of pharmacology and chemotherapy

Abbr.

Br J Pharmacol Chemother

ISSN

0366-0826

DOI

10.1111/j.1476-5381.1959.tb00937.x

Published

1959-03-00

Pages

117-24

Language

English

Region

England

NLM ID

0154627

PMCID

PMC1481815

Subset

External Links

PubMed source DOI: 10.1111/j.1476-5381.1959.tb00937.x PMC Full Text

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The extraction of human urinary kinin (substance Z) and its relation to the plasma kinins.

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