| GeneLibs

题目:: Antigen presentation by B lymphocytes to CD4+ T lymphocytes in vivo: importance for B lymphocyte and T lymphocyte activation.
作者:: Finkelman(F D),Lees(A),Morris(S C)
状态:: 发布时间1992-11-04 , 更新时间 2007-11-14
期刊:: Semin Immunol
摘要:: B lymphocytes, like macrophages and dendritic cells, can present antigen to CD4+ T cells. Antigen presentation by B cells is essential for the generation of an in vivo T cell dependent antibody response, and repeated antigen presentation by B cells to T cells is necessary to induce B cell clonal expansion. Presentation of antigen by resting B cells to unprimed T cells tolerizes T cells, while anti-IgD antibody activates B cells and allows B cell antigen presentation that productively activates T cells. However, activation is not all that is required for B cells to productively present antigen to T cells.
语言:: eng
DOI:

文献库文献相关信息