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PMID: 1354647 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.

Genomics ·Vol. 13 ·No. 4 ·1992-08-00 ·Pages 1356-8

Copeland NG, Gilbert DJ, Chrétien M, Seidah NG, Jenkins NA

Abstract

The genes for three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), have been regionally localized on chromosomes 13, 2, and 7, respectively, by interspecific backcross analysis. These results refine previous localizations by in situ hybridization as well as confirm and extend known regions of homology between mouse and human chromosomes.

MeSH Terms
Animals Chromosome Mapping Crosses, Genetic Furin Mice Mice, Inbred C57BL Polymorphism, Restriction Fragment Length Subtilisins/genetics
Chemicals
Subtilisins Furin
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Copeland N G
Mammalian Genetics Laboratory, ABL-Basic Research Program, NCI-Frederick Cancer Research and Development Center, Maryland 21702.
Gilbert D J
Chrétien M
Seidah N G
Jenkins N A
Article Info
Journal
Genomics
Abbr.
Genomics
ISSN
0888-7543
DOI
10.1016/0888-7543(92)90069-5
Published
1992-08-00
Pages
1356-8
Language
English
Region
United States
NLM ID
8800135
Subset
IM
Grants
PHS HHS · N01-C0-74101 · United States
External Links
PubMed source DOI: 10.1016/0888-7543(92)90069-5 View journal details
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