The gene for proliferating cell nuclear antigen (Pcna) maps to mouse chromosome 2.

Mammalian genome : official journal of the International Mammalian Genome Society ·Vol. 3 ·No. 5 ·1992-00-00 ·Pages 286-9

Abbott C, Pilz A, Moseley H, Peter J

Abstract

The structural gene for proliferating cell nuclear antigen (Pcna) has been mapped to mouse Chromosome (Chr) 2 by use of a PCR-based assay. With somatic cell hybrids, Pcna was mapped between the T(2;4)13H and T(2;4)1Sn breakpoints. An interspecific backcross was employed to map Pcna 1.9 +/- 1.3 cM distal to Il-lb. This was confirmed by mapping Pcna in the BXH recombinant inbred (RI) strains; no recombinants were seen between Il-la and Pcna. In addition, a PCNA-related sequence (Pcna-rsl) was mapped to Chr 19 in the BXH RI strains.

Related Genes

Pcna

MeSH Terms

Animals Base Sequence Chromosome Mapping Chromosomes Cricetinae Crosses, Genetic Genes/genetics Hybrid Cells Mice Mice, Inbred Strains Molecular Sequence Data Nuclear Proteins/genetics Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Proliferating Cell Nuclear Antigen

Chemicals

Nuclear Proteins Proliferating Cell Nuclear Antigen

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Abbott C

Department of Genetics and Biometry, University College London, UK.

Pilz A

Moseley H

Peter J

References (14)

14 references, click to expand

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Article Info

Journal

Mammalian genome : official journal of the International Mammalian Genome Society

Abbr.

Mamm Genome

ISSN

0938-8990

DOI

10.1007/BF00292157

Published

1992-00-00

Pages

286-9

Language

English

Region

United States

NLM ID

9100916

Subset

External Links

PubMed source DOI: 10.1007/BF00292157 View journal details

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The gene for proliferating cell nuclear antigen (Pcna) maps to mouse chromosome 2.

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