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PMID: 13475606 Published · ppublish English Journal Article

Macroglobulinemia. I. The antigenic relationship of pathological macroglobulins to normal gamma-globulins.

The Journal of experimental medicine ·Vol. 106 ·No. 4 ·1957-10-01 ·Pages 467-76

KORNGOLD L, VAN LEEUWEN G

Abstract

Highly purified pathological macroglobulins, which had been characterized electrophoretically and in the ultracentrifuge, were studied by the Ouchterlony gel diffusion technique. These macroglobulins were shown to be antigenically related to normal gamma(1)-macroglobulin (19S) as well as the 7S gamma-globulins. The pathological macroglobulins differ among each other and they are antigenically deficient when compared with the normal macroglobulin. There is no correlation between the macroglobulin's antigenic structure and its physico-chemical properties.

Keywords
GAMMA GLOBULIN SERUM GLOBULIN
MeSH Terms
Antigens Immunoglobulin G Macroglobulins Serum Globulins Waldenstrom Macroglobulinemia gamma-Globulins
Chemicals
Antigens Immunoglobulin G Macroglobulins Serum Globulins gamma-Globulins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
KORNGOLD L
VAN LEEUWEN G
References (18)
18 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1957-10-01
Pages
467-76
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2136814
Subset
OM
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