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PMID: 13438899 Published · ppublish English Journal Article

An electron microscope study of the morphology and distribution of the intracytoplasmic virus-like particles of Ehrlich ascites tumor cells.

The Journal of biophysical and biochemical cytology ·Vol. 3 ·No. 2 ·1957-03-25 ·Pages 161-70

ADAMS WR, PRINCE AM

Abstract

Electron microscope studies of eight different sublines of Ehrlich ascites tumor cells which had not, as far as could be determined, come in contact with any known virus, revealed dense particles measuring approximately 55 to 70 mmicro in diameter, both within and attached to the wall of cytoplasmic vesicles identified as the endoplasmic reticulum. All tumor sublines contained significant numbers of particles and revealed no qualitative or quantitative differences in particle morphology or distribution. It is concluded that these structures are a constant morphological component of the Ehrlich ascites tumor and that they probably do not represent contaminating virus. Their morphology and distribution are described, and the possible interpretations of their significance are discussed.

Keywords
MICROSCOPY ELECTRON NEOPLASMS/pathology
MeSH Terms
Animals Carcinoma, Ehrlich Tumor Cytoplasmic Vesicles Electrons Microscopy Microscopy, Electron Neoplasms/pathology Research Viruses
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
ADAMS W R
PRINCE A M
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22 references, click to expand
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Article Info
Journal
The Journal of biophysical and biochemical cytology
Abbr.
J Biophys Biochem Cytol
ISSN
0095-9901
DOI
10.1083/jcb.3.2.161
Published
1957-03-25
Pages
161-70
Language
English
Region
United States
NLM ID
17840020R
PMCID
PMC2224075
Subset
OM
External Links
PubMed source DOI: 10.1083/jcb.3.2.161 PMC Full Text
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