Apparent inhibition of liver insulinase activity by serum and serum fractions containing insulin-binding antibody.

The Journal of clinical investigation ·Vol. 36 ·No. 5 ·1957-05-00 ·Pages 648-55

YALOW RS, BERSON SA

Abstract

暂无摘要

Keywords

ANTIBODIES ENZYMES INSULIN/in blood LIVER/metabolism

MeSH Terms

Antibodies Enzymes Immunoglobulins Insulin/blood Insulysin Liver/metabolism Phosphorylation

Chemicals

Antibodies Enzymes Immunoglobulins Insulin Insulysin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

YALOW R S

BERSON S A

References (11)

11 references, click to expand

Insulin-I131 metabolism in human subjects: demonstration of insulin binding globulin in the circulation of insulin treated subjects.
J Clin Invest. 1956 Feb;35(2):170-90 PMID: 13286336
The destruction of I131-labeled insulin by rat liver extracts.
J Biol Chem. 1955 May;214(1):397-408 PMID: 14367397
Localization of an insulin-neutralizing factor by zone electrophoresis in a serum of an insulin-resistant patient.
J Lab Clin Med. 1955 May;45(5):765-70 PMID: 14368044
Insulin and adrenocorticotropin labelled with radio-iodine.
Endocrinology. 1951 Mar;48(3):277-83 PMID: 14822937
Distribution of blocking antibody in human serum proteins fractionated by electrophoresis-convection.
J Immunol. 1955 May;74(5):329-39 PMID: 14367820
In vivo and in vitro metabolism of insulin-I 131 and glucagon-I 131 in normal and cortisone-treated rabbits.
J Lab Clin Med. 1957 Mar;49(3):331-42 PMID: 13406365
Inhibition of insulin action by serum gamma globulin.
J Lab Clin Med. 1956 Jun;47(6):844-61 PMID: 13319896
Ethanol fractionation of plasma and electrophoretic identification of insulin-binding antibody.
J Clin Invest. 1957 May;36(5):642-7 PMID: 13428852
Insulin distribution and degradation.
Metabolism. 1956 Mar;5(2):128-37 PMID: 13296873
Insulin-neutralizing activity of gamma-globulins derived from the serum of an insulin-resistant patient.
Lancet. 1952 Jun 14;1(6720):1192-3 PMID: 14939753
Chemical, clinical and immunological studies on the products of human plasma fractionation XL. Quantitative separation and determination of the protein components in small amounts of normal human plasma.
J Clin Invest. 1951 Jan;30(1):99-111 PMID: 14803564

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103465

Published

1957-05-00

Pages

648-55

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC441732

Subset

External Links

PubMed source DOI: 10.1172/JCI103465 PMC Full Text View journal details

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Apparent inhibition of liver insulinase activity by serum and serum fractions containing insulin-binding antibody.

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