Effects of ionic strength of immersion medium on the structure of peripheral nerve myelin.

The Journal of biophysical and biochemical cytology ·Vol. 3 ·No. 1 ·1957-01-25 ·Pages 89-94

FINEAN JB, MILLINGTON PF

Abstract

A study of the effects of hypertonic solutions on the structure of peripheral nerve myelin reveals an expansion rather than a contraction of the layer spacing. This suggests the absence of "free" water between the myelin layers. Hypotonic solutions bring about a change in radial repeat period from 171 A to 250 to 270 A. These findings are of significance in relation to the structure of myelin.

Keywords

NERVES PERIPHERAL/anatomy and histology SODIUM CHLORIDE/effects

MeSH Terms

Histological Techniques Hypotonic Solutions Myelin Sheath Osmolar Concentration Peripheral Nerves/anatomy & histology Sodium Chloride/pharmacology

Chemicals

Hypotonic Solutions Sodium Chloride

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

FINEAN J B

MILLINGTON P F

References (3)

3 references, click to expand

Further observations on the structure of myelin.
Exp Cell Res. 1953 Sep;5(1):202-15 PMID: 13083630
X-ray analysis of the structure of peripheral nerve myelin.
Nature. 1954 Mar 20;173(4403):549-50 PMID: 13154380
The formation from the Schwann cell surface of myelin in the peripheral nerves of chick embryos.
Exp Cell Res. 1954 Nov;7(2):558-62 PMID: 13220597

Article Info

Journal

The Journal of biophysical and biochemical cytology

Abbr.

J Biophys Biochem Cytol

ISSN

0095-9901

DOI

10.1083/jcb.3.1.89

Published

1957-01-25

Pages

89-94

Language

English

Region

United States

NLM ID

17840020R

PMCID

PMC2224018

Subset

External Links

PubMed source DOI: 10.1083/jcb.3.1.89 PMC Full Text

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Effects of ionic strength of immersion medium on the structure of peripheral nerve myelin.

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