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PMID: 1334904 Published · ppublish English Journal Article

The role of the transposable element hobo in the origin of endemic inversions in wild populations of Drosophila melanogaster.

Genetica ·Vol. 86 ·No. 1-3 ·1992-00-00 ·Pages 113-26

Lyttle TW, Haymer DS

Abstract

Evidence from in situ hybridizations of DNA from the transposable element hobo to polytene salivary gland chromosome squashes reveals that hobo occupies both cytological breakpoints of three of four endemic inversions sampled from natural populations of Drosophila melanogaster in the Hawaiian islands. The fourth endemic inversion has a single hobo insert at one breakpoint. Cosmopolitan inversions on the same chromosomes do not show this association. Frequencies of both endemic and cosmopolitan inversions in Hawaiian populations fall in ranges typical for natural populations of D. melanogaster sampled worldwide, suggesting that these results may be typical of other regions besides Hawaii. This appears to be the first direct demonstration that transposable elements are responsible for causing specific rearrangements found in nature; consequently, it is also the first direct demonstration that chromosome rearrangements can arise in nature in a manner predicted by results of hybrid dysgenic crosses in the laboratory. Possible population genetic and evolutionary consequences are discussed.

MeSH Terms
Animals Chromosome Inversion Chromosomes/ultrastructure DNA Transposable Elements Drosophila melanogaster/genetics Female Genetics, Population Hawaii Hybridization, Genetic/genetics In Situ Hybridization Polymorphism, Genetic Reproduction/genetics Species Specificity
Chemicals
DNA Transposable Elements
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lyttle T W
Department of Genetics and Molecular Biology, University of Hawaii, Honolulu 96822.
Haymer D S
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Article Info
Journal
Genetica
Abbr.
Genetica
ISSN
0016-6707
DOI
10.1007/BF00133715
Published
1992-00-00
Pages
113-26
Language
English
Region
Netherlands
NLM ID
0370740
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00133715 View journal details
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