Differential splicing of Epstein-Barr virus immediate-early RNA.

Journal of virology ·Vol. 66 ·No. 10 ·1992-10-00 ·Pages 6233-6

Lau R, Packham G, Farrell PJ

Abstract

A variant form of splicing of RNA crossing the Epstein-Barr virus (EBV) BZLF1 gene was observed in the late productive cycle of EBV. This splice omits the middle exon of BZLF1 and joins the outer two exons of BZLF1 in frame, but the shortened form of BZLF1 protein (Z delta) could not be detected in natural EBV infections.

Related Genes

BZLF1

MeSH Terms

Blotting, Western Cell Line DNA DNA-Binding Proteins/genetics Exons Herpesvirus 4, Human/genetics,metabolism,physiology Polymerase Chain Reaction RNA Splicing RNA, Viral/genetics,metabolism Trans-Activators Viral Proteins/genetics Virus Replication

Chemicals

BZLF1 protein, Herpesvirus 4, Human DNA-Binding Proteins RNA, Viral Trans-Activators Viral Proteins DNA

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Lau R

Ludwig Institute for Cancer Research, St. Mary's Hospital Medical School, London, United Kingdom.

Packham G

Farrell P J

References (12)

12 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.66.10.6233-6236.1992

Published

1992-10-00

Pages

6233-6

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC283679

Subset

External Links

PubMed source DOI: 10.1128/JVI.66.10.6233-6236.1992 PMC Full Text View journal details

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Differential splicing of Epstein-Barr virus immediate-early RNA.

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