Vitrosin: a member of the collagen class.

The Journal of biophysical and biochemical cytology ·Vol. 1 ·No. 3 ·1955-05-25 ·Pages 215-20

GROSS J, MATOLTSY G, COHEN C

Abstract

Vitrosin, a fibrous protein obtained from the vitreous humor of the eye in the form of an indefinitely long fibril about 100 to 150 A in diameter, has been identified as a member of the collagen class of proteins. It is characterized by the collagen wide-angle x-ray diffraction pattern, and axial periodicity of about 640 A determined by electron microscopy and small-angle x-ray diffraction, an amino acid pattern characteristic of collagen as determined by paper chromatography, and a hydroxyproline and glycine content also typical of collagen. The glycine-hydroxyproline ratio is somewhat lower than that for most vertebrate collagens.

Keywords

PROTEINS VITREOUS BODY

MeSH Terms

Amino Acids Collagen Hydroxyproline Microscopy, Electron Proteins Vitreous Body X-Ray Diffraction

Chemicals

Amino Acids Proteins Collagen Hydroxyproline

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

GROSS J

MATOLTSY G

COHEN C

References (13)

13 references, click to expand

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Biochim Biophys Acta. 1953 Jul;11(3):326-8 PMID: 13093738
Some factors involved in the fibrogenesis of collagen in vitro.
Proc Soc Exp Biol Med. 1952 Jul;80(3):462-5 PMID: 14949085
[Structure of the fresh vitreous body; phase contrast, dark field, and immersion studies with the ultramicroscope].
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The determination of hydroxyproline.
J Biol Chem. 1950 May;184(1):299-306 PMID: 15421999
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Article Info

Journal

The Journal of biophysical and biochemical cytology

Abbr.

J Biophys Biochem Cytol

ISSN

0095-9901

DOI

10.1083/jcb.1.3.215

Published

1955-05-25

Pages

215-20

Language

English

Region

United States

NLM ID

17840020R

PMCID

PMC2223808

Subset

External Links

PubMed source DOI: 10.1083/jcb.1.3.215 PMC Full Text

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