The uppermost cells of the root and shoot apical meristems are considered as stem cells. They are similar, in many features, to the stem cells of animals. But, unlike animals, the stem cells can repeatedly arise in plants during morphogenesis and regeneration or in tissue culture from actively dividing or differentiated cells. When the stem cells are removed, they can be repeatedly restored from the actively dividing cells. The maintenance of the population of stem cells is determined by interaction between the stem cells and actively dividing cells located below according to the feedback principle. The protein synthesized in the stem cells determines how the lower located cells affect the stem cells. Specificity of stem cell identification in plants is discussed.