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PMID: 12939167 Published · ppublish English Comment Journal Article Review

Calcium signalling: NAADP comes out of the shadows.

The Biochemical journal ·Vol. 373 ·No. Pt 2 ·2003-07-15 ·Pages e3-4

Rutter GA

Abstract

The molecular mechanisms through which extracellular stimuli mobilize intracellular Ca(2+) stores are still incompletely understood. Recent work suggests that nicotinic acid-adenine dinucleotide phosphate (NAADP) can finally join the ranks of genuine Ca(2+)-mobilizing second messengers.

MeSH Terms
Animals B-Lymphocytes/physiology Calcium Signaling/physiology Humans Lymphocyte Activation/physiology NADP/analogs & derivatives,physiology Second Messenger Systems/physiology T-Lymphocytes/physiology
Chemicals
NADP NAADP
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Rutter Guy A
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University of Bristol, University Walk, UK. g.a.rutter@bris.ac.uk
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/BJ20030472COM
Email
g.a.rutter@bris.ac.uk
Published
2003-07-15
Pages
e3-4
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1223522
Subset
IM
Corrections
CommentOn
PMID: 12749764
External Links
PubMed source DOI: 10.1042/BJ20030472COM PMC Full Text View journal details
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