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PMID: 12824358 Published · ppublish English Journal Article

MAVID multiple alignment server.

Nucleic acids research ·Vol. 31 ·No. 13 ·2003-07-01 ·Pages 3525-6

Bray N, Pachter L

Abstract

MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID web server allows biomedical researchers to quickly obtain multiple alignments for genomic sequences and to subsequently analyse the alignments for conserved regions. MAVID has been successfully used for the alignment of closely related species such as primates and also for the alignment of more distant organisms such as human and fugu. The server is fast, capable of aligning hundreds of kilobases in less than a minute. The multiple alignment is used to build a phylogenetic tree for the sequences, which is subsequently used as a basis for identifying conserved regions in the alignment. The server can be accessed at http://baboon.math.berkeley.edu/mavid/.

MeSH Terms
Animals Base Sequence Conserved Sequence Genomics/methods Humans Internet Mice Molecular Sequence Data Phylogeny Rats Sequence Alignment/methods Sequence Analysis, DNA/methods Software Takifugu/genetics
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bray Nicolas
Department of Mathematics, 970 Evans Hall, UC Berkeley, Berkeley, CA 94720, USA.
Pachter Lior
References (6)
6 references, click to expand
  1. AVID: A global alignment program.
    Genome Res. 2003 Jan;13(1):97-102 PMID: 12529311
  2. PipMaker--a web server for aligning two genomic DNA sequences.
    Genome Res. 2000 Apr;10(4):577-86 PMID: 10779500
  3. Initial sequencing and comparative analysis of the mouse genome.
    Nature. 2002 Dec 5;420(6915):520-62 PMID: 12466850
  4. VISTA : visualizing global DNA sequence alignments of arbitrary length.
    Bioinformatics. 2000 Nov;16(11):1046-7 PMID: 11159318
  5. ATV: display and manipulation of annotated phylogenetic trees.
    Bioinformatics. 2001 Apr;17(4):383-4 PMID: 11301314
  6. Phylogenetic shadowing of primate sequences to find functional regions of the human genome.
    Science. 2003 Feb 28;299(5611):1391-4 PMID: 12610304
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2003-07-01
Pages
3525-6
Language
English
Region
England
NLM ID
0411011
PMCID
PMC169029
Subset
IM
Analysis Services
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