| GeneLibs

题目:: [The immunological synapse: an exclusive zone for directed cell death after specific recognition].
作者:: Reits(E),Neefjes(J)
状态:: 发布时间2003-06-25 , 更新时间 2006-11-15
期刊:: Ned Tijdschr Geneeskd
摘要:: Cytotoxic T lymphocytes or killer cells are an important part of the immune system. These cells move through the body while their T cell receptors initiate low affinity contacts with MHC class I proteins (also termed transplantation antigens) on other cells. If there is a specific interaction between the T cell receptor and MHC class I molecule, then that cell is killed. This happens with virus-infected cells but also with tumour cells, during transplant rejection and in various autoimmune diseases. The immunological synapse is a sealed area generated by the killer cell in order to selectively kill a particular cell. The cytotoxic content of the killer cell is released into this area.
语言:: dut
DOI:

文献库文献相关信息