Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis.

Animals Antioxidants/chemistry Cell Nucleus/metabolism DNA-Binding Proteins/metabolism Gene Expression Regulation Humans Mice Models, Biological Models, Genetic NAD(P)H Dehydrogenase (Quinone)/metabolism NF-E2-Related Factor 2 Neoplasms/metabolism Oxygen/metabolism Protein Conformation Protein Structure, Tertiary Reactive Oxygen Species Trans-Activators/metabolism

Antioxidants DNA-Binding Proteins NF-E2-Related Factor 2 NFE2L2 protein, human Nfe2l2 protein, mouse Reactive Oxygen Species Trans-Activators NAD(P)H Dehydrogenase (Quinone) Oxygen