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PMID: 12790531 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

C-Nucleosidations with 2,6-diamino-5,8-diaza-7,9-dicarba-purine.

Organic letters ·Vol. 5 ·No. 12 ·2003-06-12 ·Pages 2071-4

Han B, Wang Z, Jaun B, Krishnamurthy R, Eschenmoser A

Abstract

[structure: see text] Endocyclic iminium ions derived from l-4-amino-threose derivatives smoothly react with 2,6-diamino-5,8-diaza-7,9-dicarba-purine to give corresponding C(9)-nucleosides in high yields.

MeSH Terms

2-Aminopurine/analogs & derivatives,chemistry Aza Compounds/chemistry Imines/chemistry Purine Nucleosides/chemical synthesis Purines/chemistry Tetroses/chemistry

Chemicals

2,6-diamino-5,8-diaza-7,9-dicarba-purine Aza Compounds Imines Purine Nucleosides Purines Tetroses 2-Aminopurine 2,6-diaminopurine erythrose

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Han Bo

The Skaggs Institute for Chemical Biology at the Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Wang Zhijun

Jaun Bernhard

Krishnamurthy Ramanarayanan

Eschenmoser Albert

Article Info

Journal

Organic letters

Abbr.

Org Lett

ISSN

1523-7060

DOI

10.1021/ol030043v

Published

2003-06-12

Pages

2071-4

Language

English

Region

United States

NLM ID

100890393

Subset

External Links

PubMed source DOI: 10.1021/ol030043v View journal details

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