A matter of life and death: cardiac myocyte apoptosis and regeneration.

The Journal of clinical investigation ·Vol. 111 ·No. 10 ·2003-05-00 ·Pages 1457-9

Nadal-Ginard B, Kajstura J, Anversa P, Leri A

Abstract

暂无摘要

MeSH Terms

Animals Apoptosis Cardiomyopathy, Dilated/etiology,pathology,physiopathology Caspases Disease Models, Animal Heart/physiology Mice Mice, Transgenic Myocytes, Cardiac/pathology Regeneration

Chemicals

Caspases

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Nadal-Ginard Bernardo

Cardiovascular Research Institute, Department of Medicine, New York Medical College, Valhalla, New York 10595, USA. b_nadal-ginard@nymc.edu

Kajstura Jan

Anversa Piero

Leri Annarosa

References (23)

23 references, click to expand

Animal models for mitochondrial disease.
Methods Mol Biol. 2002;197:3-54 PMID: 12013805
Myocyte proliferation in end-stage cardiac failure in humans.
Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8801-5 PMID: 9671759
Myocyte death in the failing human heart is gender dependent.
Circ Res. 1999 Oct 29;85(9):856-66 PMID: 10532954
Genetic dissection of cardiac growth control pathways.
Annu Rev Physiol. 2000;62:289-319 PMID: 10845093
Apoptosis and heart failure: A critical review of the literature.
Circ Res. 2000 Jun 9;86(11):1107-13 PMID: 10850960
Models of dilated cardiomyopathy in the mouse and the hamster.
Curr Opin Cardiol. 2000 May;15(3):197-201 PMID: 10952428
Evidence that human cardiac myocytes divide after myocardial infarction.
N Engl J Med. 2001 Jun 7;344(23):1750-7 PMID: 11396441
Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy.
Circ Res. 2001 Aug 3;89(3):279-86 PMID: 11485979
From the sarcomere to the nucleus: role of genetics and signaling in structural heart disease.
Annu Rev Genomics Hum Genet. 2000;1:179-223 PMID: 11701629
Chimerism of the transplanted heart.
N Engl J Med. 2002 Jan 3;346(1):5-15 PMID: 11777997
Myocyte renewal and ventricular remodelling.
Nature. 2002 Jan 10;415(6868):240-3 PMID: 11805849
Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice.
Circ Res. 2002 Apr 5;90(6):641-8 PMID: 11934830
Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart.
Circ Res. 1999 May 14;84(9):1007-19 PMID: 10325238
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation.
EMBO J. 2003 Jan 2;22(1):131-9 PMID: 12505991
Myocyte death, growth, and regeneration in cardiac hypertrophy and failure.
Circ Res. 2003 Feb 7;92(2):139-50 PMID: 12574141
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy.
J Clin Invest. 2003 May;111(10):1463-74 PMID: 12750396
A mechanistic role for cardiac myocyte apoptosis in heart failure.
J Clin Invest. 2003 May;111(10):1497-504 PMID: 12750399
Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats.
Circ Res. 1990 Jul;67(1):23-34 PMID: 2364493
Chronic coronary artery constriction leads to moderate myocyte loss and left ventricular dysfunction and failure in rats.
J Clin Invest. 1992 Feb;89(2):618-29 PMID: 1531347
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.
Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5408-12 PMID: 1608949
The cellular basis of pacing-induced dilated cardiomyopathy. Myocyte cell loss and myocyte cellular reactive hypertrophy.
Circulation. 1995 Oct 15;92(8):2306-17 PMID: 7554216
Apoptosis in the failing human heart.
N Engl J Med. 1997 Apr 17;336(16):1131-41 PMID: 9099657
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy.
J Clin Invest. 1997 Oct 15;100(8):1991-9 PMID: 9329962

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI18611

b_nadal-ginard@nymc.edu

Published

2003-05-00

Pages

1457-9

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC155176

Subset

Corrections

CommentOn

PMID: 12750396

CommentOn

PMID: 12750399

External Links

PubMed source DOI: 10.1172/JCI18611 PMC Full Text View journal details

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