Isolation and N-terminal amino acid sequence of membrane-bound human HLA-A and HLA-B antigens.

Nature ·Vol. 261 ·No. 5557 ·1976-05-20 ·Pages 200-5

Bridgen J, Snary D, Crumpton MJ

Abstract

Membrane-bound HLA-A and HLA-B antigens have been extensively purified in good yield. The sequences of the N-terminal 16 amino acids have been determined using about 1 nmol of protein eluted from polyacrylamide gel after electrophoresis in sodium dodecyl sulphate.

MeSH Terms

Amino Acid Sequence Cell Line Cell Membrane/immunology HLA Antigens/isolation & purification Histocompatibility Antigens/isolation & purification Polymorphism, Genetic

Chemicals

HLA Antigens Histocompatibility Antigens

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bridgen J

Snary D

Crumpton M J

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/261200a0

Published

1976-05-20

Pages

200-5

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/261200a0 View journal details

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Isolation and N-terminal amino acid sequence of membrane-bound human HLA-A and HLA-B antigens.

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