Motheater: an immunodeficient mouse with markedly less ability to survive that the nude mouse in a germfree environment.

Journal of immunology (Baltimore, Md. : 1950) ·Vol. 116 ·No. 5 ·1976-05-00 ·Pages 1496-7

Lutzner MA, Hansen CT

Abstract

The motheaten mouse is an immunodeficient mutant which has been found to have elevated immunoglobulin levels, to exhibit autoimmunity, and early death. Since survival is not improved by a germfree environment, it appears that some mechanism other than infection results in its early demise.

MeSH Terms

Animals Germ-Free Life Immunologic Deficiency Syndromes/mortality Lung/cytology Mice Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred CBA Mice, Nude Mutation

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Lutzner M A

Hansen C T

Article Info

Journal

Journal of immunology (Baltimore, Md. : 1950)

Abbr.

J Immunol

ISSN

0022-1767

Published

1976-05-00

Pages

1496-7

Language

English

Region

United States

NLM ID

2985117R

Subset

External Links

PubMed source View journal details

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Motheater: an immunodeficient mouse with markedly less ability to survive that the nude mouse in a germfree environment.

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