Dynactin: coordinating motors with opposite inclinations.

Current biology : CB ·Vol. 13 ·No. 8 ·2003-04-15 ·Pages R320-2

Gross SP

Abstract

In eukaryotic cells, many organelles are transported bidirectionally along microtubules by kinesin and dynein. These opposite-polarity motors appear to be coordinated to avoid interfering with each other's function. New work has provided the first molecular insight into how such coordination might occur.

MeSH Terms

Animals Dynactin Complex Microtubule-Associated Proteins/metabolism Models, Biological Molecular Motor Proteins/metabolism,physiology Organelles/metabolism,physiology

Chemicals

Dynactin Complex Microtubule-Associated Proteins Molecular Motor Proteins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Gross Steven P

Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA. sgross@uci.edu

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

sgross@uci.edu

Published

2003-04-15

Pages

R320-2

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source View journal details

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Dynactin: coordinating motors with opposite inclinations.

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