Hypoxia increases potassium efflux from mammalian myocardium.

Experientia ·Vol. 32 ·No. 4 ·1976-04-15 ·Pages 483-4

Vleugels A, Carmeliet E

Abstract

Hypoxia with or without simultaneous depletion of extracellular glucose increases 42K-efflux in cat and guinea-pig papillary muscles and bovine Purkinje fibres. The change observed in K efflux may be the result of an increase in K conductance at rest.

MeSH Terms

Animals Biological Transport Cats Cattle Guinea Pigs Hypoxia/metabolism In Vitro Techniques Myocardium/metabolism Papillary Muscles/metabolism Potassium/metabolism Purkinje Fibers/metabolism

Chemicals

Potassium

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Vleugels A

Carmeliet E

References (9)

9 references, click to expand

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Maintenance of resting potential in anoxic guinea pig ventricular muscle: electrogenic sodium pumping.
Science. 1971 May 7;172(3983):570-2 PMID: 5555077
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Arch Int Physiol Biochim. 1975 Feb;83(1):148-50 PMID: 50779
Anoxic atrial and ventricular muscle electrical activity, cell potassium, and metabolism: a comparative study.
J Mol Cell Cardiol. 1973 Apr;5(2):149-59 PMID: 4704670
Dynamic energy partition in cultured heart cells.
Cardiology. 1971;56(1):88-92 PMID: 5152764
[The action current of the myocardial fibers in oxygen deficiency].
Pflugers Arch Gesamte Physiol Menschen Tiere. 1954;260(1):40-60 PMID: 13236475
Is potassium conductance of cardiac Purkinje fibres controlled by (Ca2+)?
Nature. 1975 Jan 24;253(5489):273-4 PMID: 1113845
Electrical activity and metabolism in cardiac tissue: An experimental and theoretical study.
J Membr Biol. 1970 Dec;3(1):180-209 PMID: 24174193
The effect of 2,4-dinitrophenol on electrical and mechanical activity, metabolism and ion movements in guinea-pig ventricular muscle.
Br J Pharmacol. 1972 Apr;44(4):711-22 PMID: 5041450

Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01920810

Published

1976-04-15

Pages

483-4

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01920810

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Hypoxia increases potassium efflux from mammalian myocardium.

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