Uptake and metabolism of beta-alanine and L-carnosine by rat tissues in vitro: role in nutrition.

The American journal of physiology ·Vol. 230 ·No. 3 ·1976-03-00 ·Pages 643-51

Nutzenadel W, Scriver CR

Abstract

Uptake and metabolism of the dipeptide L-carnosine (beta-alanyl-L-histidine) and of the free amino acid beta-alanine were studied in scraped mucosal epithelium of jejunum, kidney cortex slices, and intact hemidiaphragm muscle of the rat. These preparations expose plasma membranes with various orientations to amino nitrogen nutrition.

MeSH Terms

Alanine/metabolism Amino Acids/pharmacology Aminooxyacetic Acid/pharmacology Animals Biological Transport Carnosine/metabolism Diaphragm/metabolism Dipeptides/metabolism In Vitro Techniques Intestinal Mucosa/metabolism Jejunum/metabolism Kidney Cortex/metabolism Kinetics Oligopeptides/pharmacology Rats Sodium/metabolism Time Factors

Chemicals

Amino Acids Dipeptides Oligopeptides Aminooxyacetic Acid Carnosine Sodium Alanine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nutzenadel W

Scriver C R

Article Info

Journal

The American journal of physiology

Abbr.

Am J Physiol

ISSN

0002-9513

DOI

10.1152/ajplegacy.1976.230.3.643

Published

1976-03-00

Pages

643-51

Language

English

Region

United States

NLM ID

0370511

Subset

External Links

PubMed source DOI: 10.1152/ajplegacy.1976.230.3.643 View journal details

Analysis Services

Uptake and metabolism of beta-alanine and L-carnosine by rat tissues in vitro: role in nutrition.

Contact

WeChat Official Account