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PMID: 12659113 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Physical activity, body weight, and pancreatic cancer mortality.

British journal of cancer ·Vol. 88 ·No. 5 ·2003-03-10 ·Pages 679-83

Lee IM, Sesso HD, Oguma Y, Paffenbarger RS

Abstract

In a study of 32 687 subjects with data on physical activity and body mass index (BMI) collected serially over time, we examined associations with pancreatic cancer mortality (n=212). Despite plausible biologic mechanisms, neither physical activity (multivariate relative risks for increasing levels: 1.00, 0.98, 0.92, and 1.31, respectively) nor BMI (corresponding findings: 1.00, 0.84, 1.08, and 0.99, respectively) significantly predicted pancreatic cancer mortality.

MeSH Terms
Adult Body Mass Index Body Weight Exercise Female Humans Male Middle Aged Pancreatic Neoplasms/mortality United States/epidemiology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Lee I-M
Department of Medicine, Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215, USA. ilee@rics.bwh.harvard.edu
Sesso H D
Oguma Y
Paffenbarger R S
References (25)
25 references, click to expand
  1. Effects of physical activity on insulin action and glucose tolerance in obesity.
    Med Sci Sports Exerc. 1999 Nov;31(11 Suppl):S619-23 PMID: 10593537
  2. Associations of light, moderate, and vigorous intensity physical activity with longevity. The Harvard Alumni Health Study.
    Am J Epidemiol. 2000 Feb 1;151(3):293-9 PMID: 10670554
  3. Abnormal glucose metabolism and pancreatic cancer mortality.
    JAMA. 2000 May 17;283(19):2552-8 PMID: 10815119
  4. Predictors of pancreatic cancer mortality among a large cohort of United States adults.
    Cancer Causes Control. 2000 Dec;11(10):915-23 PMID: 11142526
  5. Prevention of pancreatic cancer induction in hamsters by metformin.
    Gastroenterology. 2001 Apr;120(5):1263-70 PMID: 11266389
  6. Effects of exercise on glucose homeostasis in Type 2 diabetes mellitus.
    Med Sci Sports Exerc. 2001 Jun;33(6 Suppl):S495-501; discussion S528-9 PMID: 11427776
  7. Physical activity, obesity, height, and the risk of pancreatic cancer.
    JAMA. 2001 Aug 22-29;286(8):921-9 PMID: 11509056
  8. Dietary sugar, glycemic load, and pancreatic cancer risk in a prospective study.
    J Natl Cancer Inst. 2002 Sep 4;94(17):1293-300 PMID: 12208894
  9. A collaborative case-control study of nutrient intake and pancreatic cancer within the search programme.
    Int J Cancer. 1992 May 28;51(3):365-72 PMID: 1317361
  10. Time trends in physical activity among college alumni, 1962-1988.
    Am J Epidemiol. 1992 Apr 15;135(8):915-25 PMID: 1585904
  11. Reliability and physiologic correlates of the Harvard Alumni Activity Survey in a general population.
    J Clin Epidemiol. 1991;44(12):1319-26 PMID: 1753263
  12. Physical activity on the job and cancer in Missouri.
    Am J Public Health. 1991 May;81(5):639-42 PMID: 2014869
  13. Validation and comparison of eight physical activity questionnaires.
    Epidemiology. 1990 Jan;1(1):65-71 PMID: 2081242
  14. Validity of self-reported waist and hip circumferences in men and women.
    Epidemiology. 1990 Nov;1(6):466-73 PMID: 2090285
  15. Mortality by relative weight and exercise.
    Cancer. 1988 Oct 15;62(8 Suppl):1844-50 PMID: 3167802
  16. The mortality experience of major-league baseball players.
    N Engl J Med. 1988 May 12;318(19):1278-80 PMID: 3362185
  17. Physical activity and incidence of cancer in diverse populations: a preliminary report.
    Am J Clin Nutr. 1987 Jan;45(1 Suppl):312-7 PMID: 3799521
  18. Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis.
    JAMA. 1995 May 24-31;273(20):1605-9 PMID: 7745774
  19. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine.
    JAMA. 1995 Feb 1;273(5):402-7 PMID: 7823386
  20. Treatment and survival in 13,560 patients with pancreatic cancer, and incidence of the disease, in the West Midlands: an epidemiological study.
    Br J Surg. 1995 Jan;82(1):111-5 PMID: 7881926
  21. Accuracy of the College Alumnus Physical Activity Questionnaire.
    J Clin Epidemiol. 1993 Dec;46(12):1403-11 PMID: 8263567
  22. Dietary intake as a risk factor for cancer of the exocrine pancreas.
    Cancer Epidemiol Biomarkers Prev. 1993 Nov-Dec;2(6):513-8 PMID: 8268766
  23. Compendium of physical activities: classification of energy costs of human physical activities.
    Med Sci Sports Exerc. 1993 Jan;25(1):71-80 PMID: 8292105
  24. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee.
    World Health Organ Tech Rep Ser. 1995;854:1-452 PMID: 8594834
  25. Insulin promotes pancreatic cancer: evidence for endocrine influence on exocrine pancreatic tumors.
    J Surg Res. 1996 Jun;63(1):310-3 PMID: 8661216
Article Info
Journal
British journal of cancer
Abbr.
Br J Cancer
ISSN
0007-0920
DOI
10.1038/sj.bjc.6600782
Email
ilee@rics.bwh.harvard.edu
Published
2003-03-10
Pages
679-83
Language
English
Region
England
NLM ID
0370635
PMCID
PMC2376353
Subset
IM
Grants
NCI NIH HHS · R03 CA091213 · United States
NCI NIH HHS · CA-91213 · United States
NHLBI NIH HHS · HL-67429 · United States
External Links
PubMed source DOI: 10.1038/sj.bjc.6600782 PMC Full Text View journal details
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