Home LiteratureArticle Details
PMID: 12648679 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell.

Current opinion in cell biology ·Vol. 15 ·No. 2 ·2003-04-00 ·Pages 221-31

Tyson JJ, Chen KC, Novak B

Abstract

The physiological responses of cells to external and internal stimuli are governed by genes and proteins interacting in complex networks whose dynamical properties are impossible to understand by intuitive reasoning alone. Recent advances by theoretical biologists have demonstrated that molecular regulatory networks can be accurately modeled in mathematical terms. These models shed light on the design principles of biological control systems and make predictions that have been verified experimentally.

MeSH Terms
Animals Biological Clocks/physiology Eukaryotic Cells/metabolism Feedback, Physiological/physiology Genomics/methods,trends Humans Models, Biological Proteomics/methods,trends Signal Transduction/physiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Tyson John J
Department of Biology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. tyson@vt.edu
Chen Katherine C
Novak Bela
Article Info
Journal
Current opinion in cell biology
Abbr.
Curr Opin Cell Biol
ISSN
0955-0674
Published
2003-04-00
Pages
221-31
Language
English
Region
England
NLM ID
8913428
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com