-
Oligomerization of G-protein-coupled transmitter receptors.
Nat Rev Neurosci. 2001 Apr;2(4):274-86
PMID: 11283750
-
Activation of rhodopsin: new insights from structural and biochemical studies.
Trends Biochem Sci. 2001 May;26(5):318-24
PMID: 11343925
-
Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells.
Life Sci. 2001 Apr 6;68(19-20):2243-50
PMID: 11358333
-
Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors.
Mol Pharmacol. 2001 Jul;60(1):1-19
PMID: 11408595
-
Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
Biochemistry. 2001 Jul 3;40(26):7761-72
PMID: 11425302
-
Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.
Nature. 2001 Jul 5;412(6842):86-90
PMID: 11452312
-
A functional rhodopsin-green fluorescent protein fusion protein localizes correctly in transgenic Xenopus laevis retinal rods and is expressed in a time-dependent pattern.
J Biol Chem. 2001 Jul 27;276(30):28242-51
PMID: 11350960
-
Crystal structure of rhodopsin: implications for vision and beyond.
Curr Opin Struct Biol. 2001 Aug;11(4):420-6
PMID: 11495733
-
Modeling the 3D structure of GPCRs from sequence.
Med Res Rev. 2001 Sep;21(5):472-83
PMID: 11579443
-
Rhodopsin: structural basis of molecular physiology.
Physiol Rev. 2001 Oct;81(4):1659-88
PMID: 11581499
-
Three-dimensional representations of G protein-coupled receptor structures and mechanisms.
Methods Enzymol. 2002;343:329-71
PMID: 11665578
-
Dimerization of G-protein-coupled receptors.
J Med Chem. 2001 Dec 20;44(26):4595-614
PMID: 11741478
-
The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop.
Annu Rev Pharmacol Toxicol. 2002;42:437-67
PMID: 11807179
-
G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction.
Cell Signal. 2002 Apr;14(4):297-309
PMID: 11858937
-
G-protein-coupled receptor dimerization: modulation of receptor function.
Pharmacol Ther. 2001 Nov-Dec;92(2-3):71-87
PMID: 11916530
-
Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation.
Mol Pharmacol. 2002 May;61(5):1025-32
PMID: 11961120
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.
Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5982-7
PMID: 11972040
-
The structural basis of G-protein-coupled receptor function and dysfunction in human diseases.
Rev Physiol Biochem Pharmacol. 2002;144:143-227
PMID: 11987825
-
Seven-transmembrane receptors.
Nat Rev Mol Cell Biol. 2002 Sep;3(9):639-50
PMID: 12209124
-
G-protein-coupled receptor oligomerization and its potential for drug discovery.
Nat Rev Drug Discov. 2002 Oct;1(10):808-20
PMID: 12360258
-
Prediction of structure and function of G protein-coupled receptors.
Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12622-7
PMID: 12351677
-
Drug design strategies for targeting G-protein-coupled receptors.
Chembiochem. 2002 Oct 4;3(10):928-44
PMID: 12362358
-
Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors.
Naunyn Schmiedebergs Arch Pharmacol. 2002 Nov;366(5):381-416
PMID: 12382069
-
Crystal structure of rhodopsin: a template for cone visual pigments and other G protein-coupled receptors.
Biochim Biophys Acta. 2002 Oct 11;1565(2):168-82
PMID: 12409193
-
Atomic-force microscopy: Rhodopsin dimers in native disc membranes.
Nature. 2003 Jan 9;421(6919):127-8
PMID: 12520290
-
G protein-coupled receptor rhodopsin: a prospectus.
Annu Rev Physiol. 2003;65:851-79
PMID: 12471166
-
G protein-coupled receptor drug discovery: implications from the crystal structure of rhodopsin.
Curr Opin Drug Discov Devel. 2001 Sep;4(5):561-74
PMID: 12825452
-
The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors.
Annu Rev Biophys Biomol Struct. 2003;32:375-97
PMID: 12574068
-
Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.
Proc Natl Acad Sci U S A. 1986 May;83(9):2797-801
PMID: 2871555
-
Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase.
Nature. 1986 Jun 26-Jul 2;321(6073):869-72
PMID: 3014340
-
Purification and characterization of the beta-adrenergic receptor kinase.
J Biol Chem. 1987 Jul 5;262(19):9026-32
PMID: 3036840
-
Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase.
J Biol Chem. 1987 Dec 25;262(36):17251-3
PMID: 2826414
-
G-protein-coupled receptor kinases.
Trends Biochem Sci. 1991 Oct;16(10):387-91
PMID: 1664548
-
A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment.
J Neurosci. 1994 Oct;14(10):5818-33
PMID: 7523628
-
In vivo assembly of rhodopsin from expressed polypeptide fragments.
Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3204-8
PMID: 7724540
-
G protein-coupled receptor structure and function: the impact of disease-causing mutations.
Baillieres Clin Endocrinol Metab. 1995 Jul;9(3):427-51
PMID: 7575327
-
MOLMOL: a program for display and analysis of macromolecular structures.
J Mol Graph. 1996 Feb;14(1):51-5, 29-32
PMID: 8744573
-
Functional and structural complexity of signal transduction via G-protein-coupled receptors.
Annu Rev Neurosci. 1997;20:399-427
PMID: 9056720
-
GPCRDB: an information system for G protein-coupled receptors.
Nucleic Acids Res. 1998 Jan 1;26(1):275-9
PMID: 9399852
-
Null mutation in the rhodopsin kinase gene slows recovery kinetics of rod and cone phototransduction in man.
Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):328-33
PMID: 9419375
-
Highly selective separation of rhodopsin from bovine rod outer segment membranes using combination of divalent cation and alkyl(thio)glucoside.
Photochem Photobiol. 1998 May;67(5):495-9
PMID: 9613234
-
A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif.
Biophys J. 1998 Aug;75(2):601-11
PMID: 9675163
-
G protein-coupled receptor kinases.
Annu Rev Biochem. 1998;67:653-92
PMID: 9759500
-
Molecular tinkering of G protein-coupled receptors: an evolutionary success.
EMBO J. 1999 Apr 1;18(7):1723-9
PMID: 10202136
-
Five-transmembrane domains appear sufficient for a G protein-coupled receptor: functional five-transmembrane domain chemokine receptors.
Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):7922-7
PMID: 10393923
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors.
Endocr Rev. 2000 Feb;21(1):90-113
PMID: 10696571
-
Molecular genetics of human retinal disease.
Annu Rev Genet. 1999;33:89-131
PMID: 10690405
-
Folding and assembly in rhodopsin. Effect of mutations in the sixth transmembrane helix on the conformation of the third cytoplasmic loop.
J Biol Chem. 1999 Jul 23;274(30):21437-42
PMID: 10409707
-
Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET).
Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3684-9
PMID: 10725388
-
G-protein-coupled receptors function as oligomers in vivo.
Curr Biol. 2000 Mar 23;10(6):341-4
PMID: 10744981
-
X-Ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles.
J Struct Biol. 2000 May;130(1):73-80
PMID: 10806093
-
Molecular manipulation of G-protein-coupled receptors: a new avenue into drug discovery.
Curr Med Chem. 2000 Sep;7(9):889-96
PMID: 10911021
-
Crystal structure of rhodopsin: A G protein-coupled receptor.
Science. 2000 Aug 4;289(5480):739-45
PMID: 10926528
-
Dimerization and domain swapping in G-protein-coupled receptors: a computational study.
Neuropsychopharmacology. 2000 Oct;23(4 Suppl):S60-77
PMID: 11008068
-
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
Nature. 2000 Oct 26;407(6807):971-7
PMID: 11069170
-
Identification of an outer segment targeting signal in the COOH terminus of rhodopsin using transgenic Xenopus laevis.
J Cell Biol. 2000 Dec 25;151(7):1369-80
PMID: 11134067
-
The sequence of the human genome.
Science. 2001 Feb 16;291(5507):1304-51
PMID: 11181995
-
Initial sequencing and analysis of the human genome.
Nature. 2001 Feb 15;409(6822):860-921
PMID: 11237011
-
Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan.
Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3744-9
PMID: 11274391