Considering nuclear compartmentalization in the light of nuclear dynamics.

Cell ·Vol. 112 ·No. 4 ·2003-02-21 ·Pages 403-6

Chubb JR, Bickmore WA

Abstract

Many proteins are concentrated in compartments within the nucleus. Chromatin is also compartmentalized at different nuclear sites. However, nuclear proteins have now been shown to be highly mobile. This review considers the formation and function of nuclear compartments in a situation in which proteins are rapidly moving through the nuclear volume.

MeSH Terms

Active Transport, Cell Nucleus Animals Cell Nucleus/metabolism,ultrastructure Chromatin/metabolism Saccharomycetales/ultrastructure Transcription, Genetic

Chemicals

Chromatin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chubb Jonathan R

MRC Human Genetics Unit, Crewe Road, Edinburgh EH4 2XU, United Kingdom.

Bickmore Wendy A

Article Info

Journal

Cell

Abbr.

Cell

ISSN

0092-8674

DOI

10.1016/s0092-8674(03)00078-3

Published

2003-02-21

Pages

403-6

Language

English

Region

United States

NLM ID

0413066

Subset

External Links

PubMed source DOI: 10.1016/s0092-8674(03)00078-3 View journal details

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Considering nuclear compartmentalization in the light of nuclear dynamics.

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