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PMID: 1257744 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Human Y-chromosome-specific reiterated DNA.

Science (New York, N.Y.) ·Vol. 191 ·No. 4232 ·1976-03-19 ·Pages 1189-90

Kunkel LM, Smith KD, Boyer SH

Abstract

Radiolabeled reiterated DNA specific for the human Y chromosome has been obtained by extensive reassociations between [3H]DNA prepared from men and excess DNA from women. These highly purifed labeled sequences reassociate only with DNA from individuals with a Y chromosome. The percentage of Y-chromosome-specific DNA isolated from individuals with differing numbers of Y chromosomes is a function of the number of chromosomes present. The purifed Y-chromosome-specific sequences may represent between 7 and 11 percent of the human Y chromosome.

MeSH Terms

Base Sequence Female Genotype Humans Lymphocytes/analysis Male Nucleic Acid Denaturation

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Kunkel L M

Smith K D

Boyer S H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.1257744

Published

1976-03-19

Pages

1189-90

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.1257744 View journal details

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