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PMID: 12519993 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

BIND: the Biomolecular Interaction Network Database.

Nucleic acids research ·Vol. 31 ·No. 1 ·2003-01-01 ·Pages 248-50

Bader GD, Betel D, Hogue CW

Abstract

The Biomolecular Interaction Network Database (BIND: http://bind.ca) archives biomolecular interaction, complex and pathway information. A web-based system is available to query, view and submit records. BIND continues to grow with the addition of individual submissions as well as interaction data from the PDB and a number of large-scale interaction and complex mapping experiments using yeast two hybrid, mass spectrometry, genetic interactions and phage display. We have developed a new graphical analysis tool that provides users with a view of the domain composition of proteins in interaction and complex records to help relate functional domains to protein interactions. An interaction network clustering tool has also been developed to help focus on regions of interest. Continued input from users has helped further mature the BIND data specification, which now includes the ability to store detailed information about genetic interactions. The BIND data specification is available as ASN.1 and XML DTD.

MeSH Terms
Amino Acid Sequence Animals Computer Graphics Databases, Protein Macromolecular Substances Protein Interaction Mapping Protein Structure, Tertiary Proteins/chemistry,metabolism,physiology Sequence Alignment/methods
Chemicals
Macromolecular Substances Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Bader Gary D
Department of Biochemistry, Samuel Lunenfeld Research Institute, University of Toronto, Toronto M5G 1X5, Canada.
Betel Doron
Hogue Christopher W V
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
Published
2003-01-01
Pages
248-50
Language
English
Region
England
NLM ID
0411011
PMCID
PMC165503
Subset
IM
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