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PMID: 12433581 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Human demographic history: refining the recent African origin model.

Current opinion in genetics & development ·Vol. 12 ·No. 6 ·2002-12-00 ·Pages 675-82

Excoffier L

Abstract

Recent studies of large portions of the human genome support a recent origin of modern humans from an African stock after a bottleneck of moderate size followed by a range expansion out of Africa. Under this simple scenario, patterns of molecular diversity suggest that balancing selection could be more prevalent than positive selection in coding regions.

MeSH Terms

Africa Evolution, Molecular Genetic Variation Genetics, Population Genome, Human Humans Linkage Disequilibrium Population Dynamics Selection, Genetic

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Excoffier Laurent

Computational and Molecular Population Genetics (CMPG) Lab, Zoological Institute, University of Bern, Baltzerstrasse 6, 3012, Bern, Switzerland. Laurent.Exoffier@zoo.unibe.ch

Article Info

Journal

Current opinion in genetics & development

Abbr.

Curr Opin Genet Dev

ISSN

0959-437X

DOI

10.1016/s0959-437x(02)00350-7

laurent.exoffier@zoo.unibe.ch

Published

2002-12-00

Pages

675-82

Language

English

Region

England

NLM ID

9111375

Subset

External Links

PubMed source DOI: 10.1016/s0959-437x(02)00350-7 View journal details

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