Recognition of acetylated proteins: lessons from an ancient family of enzymes.

Structure (London, England : 1993) ·Vol. 10 ·No. 10 ·2002-10-00 ·Pages 1290-2

Tanny JC, Moazed D

Abstract

The structure of a Sir2-like enzyme in complex with an acetylated peptide substrate has been solved, and provides the first glimpse into the mechanism of substrate recognition by this highly conserved family of enzymes.

MeSH Terms

Acetylation Crystallography, X-Ray Enzymes/chemistry,metabolism Models, Molecular Protein Conformation Proteins/chemistry,metabolism

Chemicals

Enzymes Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Tanny Jason C

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

Moazed Danesh

Article Info

Journal

Structure (London, England : 1993)

Abbr.

Structure

ISSN

0969-2126

DOI

10.1016/s0969-2126(02)00862-6

Published

2002-10-00

Pages

1290-2

Language

English

Region

United States

NLM ID

101087697

Subset

External Links

PubMed source DOI: 10.1016/s0969-2126(02)00862-6 View journal details

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Recognition of acetylated proteins: lessons from an ancient family of enzymes.

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