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PMID: 12270955 Published · ppublish English Journal Article Review

Metabolic myopathy in heart failure.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society ·Vol. 17 ·2002-10-00 ·Pages 191-6

Ventura-Clapier R, De Sousa E, Veksler V

Abstract

Heart failure is a syndrome that also affects the periphery. Exercise intolerance and early fatigue seem to be linked in part to intrinsic alterations of skeletal muscle with decreases in both the production of ATP by mitochondria and the transfer of energy through the phosphotransfer kinases.

MeSH Terms
Heart Failure/metabolism,physiopathology Humans Muscle, Skeletal/blood supply,metabolism,physiopathology Neurotransmitter Agents/physiology Oxidative Stress/physiology Regional Blood Flow/physiology
Chemicals
Neurotransmitter Agents
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Ventura-Clapier Renée
U-446 INSERM, Cardiologie Cellulaire et Moléculaire, Université Paris-Sud, 92 296 Châtenay-Malabry, France.
De Sousa Elvira
Veksler Vladimir
Article Info
Journal
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
Abbr.
News Physiol Sci
ISSN
0886-1714
Published
2002-10-00
Pages
191-6
Language
English
Region
United States
NLM ID
8609378
Subset
IM
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