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PMID: 12209128 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Listening in on bacteria: acyl-homoserine lactone signalling.

Nature reviews. Molecular cell biology ·Vol. 3 ·No. 9 ·2002-09-00 ·Pages 685-95

Fuqua C, Greenberg EP

Abstract

Bacterial cell-to-cell signalling has emerged as a new area in microbiology. Individual bacterial cells communicate with each other and co-ordinate group activities. Although a lot of detail is known about the mechanisms of a few well-characterized bacterial communication systems, other systems have been discovered only recently. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs.

MeSH Terms
4-Butyrolactone/analogs & derivatives,biosynthesis,chemistry,metabolism Animals Bacteria/cytology,enzymology,metabolism,pathogenicity Biofilms Bioterrorism Luminescent Measurements Repressor Proteins/chemistry,genetics,metabolism Signal Transduction Symbiosis Trans-Activators/chemistry,genetics,metabolism
Chemicals
Repressor Proteins Trans-Activators LuxR autoinducer binding proteins homoserine lactone 4-Butyrolactone
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Fuqua Clay
Department of Biology, Indiana University, Jordan Hall 142, 1001 East 3rd Street, Bloomington, Indiana 47405, USA.
Greenberg E Peter
Article Info
Journal
Nature reviews. Molecular cell biology
Abbr.
Nat Rev Mol Cell Biol
ISSN
1471-0072
Published
2002-09-00
Pages
685-95
Language
English
Region
England
NLM ID
100962782
Subset
IM
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