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Identification of a novel nuclear domain.
J Cell Biol. 1991 Mar;112(5):785-95
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Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.
EMBO J. 1992 Feb;11(2):629-42
PMID: 1311253
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The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site.
Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1725-9
PMID: 1531875
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Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms.
Oncogene. 1992 Jun;7(6):1083-91
PMID: 1594241
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Ras mediates translation initiation factor 4E-induced malignant transformation.
Genes Dev. 1992 Sep;6(9):1631-42
PMID: 1516827
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A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies.
J Cell Sci. 1992 Apr;101 ( Pt 4):773-84
PMID: 1527179
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A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.
Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9612-6
PMID: 1384058
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Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenase.
Science. 1993 Jan 15;259(5093):365-8
PMID: 8420004
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Distribution of snRNPs, splicing factor SC-35 and actin in interphase nuclei: immunocytochemical evidence for differential distribution during changes in functional states.
J Cell Sci. 1993 Jun;105 ( Pt 2):347-57
PMID: 8408269
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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein.
Cell. 1994 Jan 28;76(2):333-43
PMID: 8293467
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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells.
Cell. 1994 Jan 28;76(2):345-56
PMID: 8293468
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Initiation factor eIF-4E of Saccharomyces cerevisiae. Distribution within the cell, binding to mRNA, and consequences of its overproduction.
J Biol Chem. 1994 Feb 25;269(8):6117-23
PMID: 8119957
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Glyceraldehyde-3-phosphate dehydrogenase selectively binds AU-rich RNA in the NAD(+)-binding region (Rossmann fold).
J Biol Chem. 1995 Feb 10;270(6):2755-63
PMID: 7531693
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PML nuclear bodies are general targets for inflammation and cell proliferation.
Cancer Res. 1995 Apr 1;55(7):1590-7
PMID: 7882370
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Characterization of a new monoclonal antibody (PG-M3) directed against the aminoterminal portion of the PML gene product: immunocytochemical evidence for high expression of PML proteins on activated macrophages, endothelial cells, and epithelia.
Blood. 1995 Apr 1;85(7):1871-80
PMID: 7535592
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The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.
EMBO J. 1995 Apr 3;14(7):1532-41
PMID: 7729428
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Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2627-32
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Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia.
Blood. 1999 May 15;93(10):3167-215
PMID: 10233871
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P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor.
Proc Natl Acad Sci U S A. 1999 May 11;96(10):5382-7
PMID: 10318892
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Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA.
J Cell Biol. 2000 Jan 24;148(2):283-92
PMID: 10648561
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RING domains: master builders of molecular scaffolds?
J Mol Biol. 2000 Feb 4;295(5):1103-12
PMID: 10653689
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The lymphocytic choriomeningitis virus RING protein Z associates with eukaryotic initiation factor 4E and selectively represses translation in a RING-dependent manner.
J Virol. 2000 Apr;74(7):3293-300
PMID: 10708446
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The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.
Oncogene. 2000 Mar 23;19(13):1623-34
PMID: 10763819
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Nuclear structure in normal and Bloom syndrome cells.
Proc Natl Acad Sci U S A. 2000 May 9;97(10):5214-9
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Review: properties and assembly mechanisms of ND10, PML bodies, or PODs.
J Struct Biol. 2000 Apr;129(2-3):278-87
PMID: 10806078
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Nuclear distribution of prothymosin alpha and parathymosin: evidence that prothymosin alpha is associated with RNA synthesis processing and parathymosin with early DNA replication.
Exp Cell Res. 2000 May 25;257(1):152-61
PMID: 10854063
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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras.
Nature. 2000 Jul 13;406(6792):207-10
PMID: 10910364
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PML is induced by oncogenic ras and promotes premature senescence.
Genes Dev. 2000 Aug 15;14(16):2015-27
PMID: 10950866
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Combinatorial roles of the nuclear receptor corepressor in transcription and development.
Cell. 2000 Sep 15;102(6):753-63
PMID: 11030619
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Cajal bodies: the first 100 years.
Annu Rev Cell Dev Biol. 2000;16:273-300
PMID: 11031238
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SUMO--nonclassical ubiquitin.
Annu Rev Cell Dev Biol. 2000;16:591-626
PMID: 11031248
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p53 binds selectively to the 5' untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4.
Mol Cell Biol. 2000 Nov;20(22):8420-31
PMID: 11046139
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ALT-associated PML bodies are present in viable cells and are enriched in cells in the G(2)/M phase of the cell cycle.
J Cell Sci. 2000 Dec;113 Pt 24:4577-85
PMID: 11082050
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Visualization of gene activity in living cells.
Nat Cell Biol. 2000 Dec;2(12):871-8
PMID: 11146650
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Exploring (novel) gene expression during retinoid-induced maturation and cell death of acute promyelocytic leukemia.
Semin Hematol. 2001 Jan;38(1):71-85
PMID: 11172541
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PML and COP1--two proteins with much in common.
Trends Biochem Sci. 2001 Jan;26(1):18-20
PMID: 11165511
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Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virus.
J Virol. 2001 Jul;75(13):6204-8
PMID: 11390623
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Immunohistochemical expression and pathogenesis of BLM in the human brain and visceral organs.
Neuropathology. 2001 Jun;21(2):123-8
PMID: 11396677
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The human interferon- and estrogen-regulated ISG20/HEM45 gene product degrades single-stranded RNA and DNA in vitro.
Biochemistry. 2001 Jun 19;40(24):7174-9
PMID: 11401564
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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation.
J Exp Med. 2001 Jun 18;193(12):1361-71
PMID: 11413191
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Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.
Mol Cell. 2001 Jun;7(6):1233-43
PMID: 11430826
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Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication.
Mol Cell. 2001 Jun;7(6):1245-54
PMID: 11430827
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PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator.
EMBO J. 2001 Jul 2;20(13):3495-505
PMID: 11432836
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Induction of the PML protein by interferons in normal and APL cells.
Leukemia. 1995 Dec;9(12):2027-33
PMID: 8609713
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Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.
Oncogene. 1995 Dec 21;11(12):2565-73
PMID: 8545113
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Analysis of the growth and transformation suppressor domains of promyelocytic leukemia gene, PML.
J Biol Chem. 1996 Jan 5;271(1):130-5
PMID: 8550548
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Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1065-70
PMID: 8577715
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Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors.
Mol Endocrinol. 1995 Dec;9(12):1791-803
PMID: 8614415
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In vivo and in vitro characterization of the B1 and B2 zinc-binding domains from the acute promyelocytic leukemia protooncoprotein PML.
Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1601-6
PMID: 8643677
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Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome.
Nature. 1996 Feb 15;379(6566):655-7
PMID: 8628401
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Exclusion of Int-6 from PML nuclear bodies by binding to the HTLV-I Tax oncoprotein.
Science. 1996 Aug 16;273(5277):951-3
PMID: 8688078
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Nuclear domain 10 (ND10) associated proteins are also present in nuclear bodies and redistribute to hundreds of nuclear sites after stress.
J Cell Biochem. 1995 Dec;59(4):498-513
PMID: 8749719
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The PML nuclear bodies: actors or extras?
Curr Opin Genet Dev. 1999 Jun;9(3):362-7
PMID: 10377280
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Evidence for functional conservation of a mammalian homologue of the light-responsive plant protein COP1.
Curr Biol. 1999 Jul 1;9(13):711-4
PMID: 10395541
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Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.
Cancer Res. 1999 Sep 1;59(17):4175-9
PMID: 10485449
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PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1.
J Cell Biol. 1999 Oct 18;147(2):221-34
PMID: 10525530
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Nuclear domains enriched in RNA 3'-processing factors associate with coiled bodies and histone genes in a cell cycle-dependent manner.
Mol Biol Cell. 1999 Nov;10(11):3815-24
PMID: 10564273
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Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.
Mol Carcinog. 1999 Dec;26(4):261-73
PMID: 10569803
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Translational regulation of ribonucleotide reductase by eukaryotic initiation factor 4E links protein synthesis to the control of DNA replication.
J Biol Chem. 1999 Dec 10;274(50):35991-8
PMID: 10585489
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The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control.
Oncogene. 1999 Nov 25;18(50):7091-100
PMID: 10597310
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Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies.
Genes Cells. 1999 Dec;4(12):743-56
PMID: 10620019
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The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells.
Br J Cancer. 2001 Jul 20;85(2):261-5
PMID: 11461087
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Accumulation and intranuclear distribution of unintegrated human immunodeficiency virus type 1 DNA.
J Virol. 2001 Aug;75(16):7683-91
PMID: 11462040
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Coupled transcription and translation within nuclei of mammalian cells.
Science. 2001 Aug 10;293(5532):1139-42
PMID: 11423616
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PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.
EMBO J. 2001 Aug 15;20(16):4547-59
PMID: 11500381
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Telomerase can inhibit the recombination-based pathway of telomere maintenance in human cells.
J Biol Chem. 2001 Aug 24;276(34):32198-203
PMID: 11395519
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Functional interaction of p53 and BLM DNA helicase in apoptosis.
J Biol Chem. 2001 Aug 31;276(35):32948-55
PMID: 11399766
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Multifunctional regulatory proteins that control gene expression in both the nucleus and the cytoplasm.
Bioessays. 2001 Sep;23(9):775-87
PMID: 11536290
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The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells.
Leukemia. 1995 Sep;9(9):1467-72
PMID: 7658713
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Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels.
J Biol Chem. 1995 Sep 8;270(36):21176-80
PMID: 7673150
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The acute promyelocytic leukaemia-associated PML gene is induced by interferon.
Oncogene. 1995 Sep 7;11(5):871-6
PMID: 7545807
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PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia.
Oncogene. 1996 Sep 5;13(5):971-82
PMID: 8806687
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PML-containing nuclear bodies: their spatial distribution in relation to other nuclear components.
J Cell Biochem. 1996 Dec 1;63(3):280-91
PMID: 8913879
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Characterisation of the PML/RAR alpha rearrangement associated with t(15;17) acute promyelocytic leukaemia.
Curr Top Microbiol Immunol. 1997;220:81-112
PMID: 9103677
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Molecular cloning of a new interferon-induced PML nuclear body-associated protein.
J Biol Chem. 1997 Aug 1;272(31):19457-63
PMID: 9235947
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Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures.
Nature. 1997 Oct 30;389(6654):971-4
PMID: 9353120
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Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein.
Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10901-6
PMID: 9380732
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The XHex homeobox gene is expressed during development of the vascular endothelium: overexpression leads to an increase in vascular endothelial cell number.
Mech Dev. 1997 Aug;66(1-2):83-93
PMID: 9376326
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Cell-cycle regulation of DNA damage-induced expression of the suppressor gene PML.
Biochem Biophys Res Commun. 1997 Nov 26;240(3):640-6
PMID: 9398618
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The promyelocytic leukemia protein PML has a pro-apoptotic activity mediated through its RING domain.
FEBS Lett. 1997 Nov 24;418(1-2):30-4
PMID: 9414089
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An arenavirus RING (zinc-binding) protein binds the oncoprotein promyelocyte leukemia protein (PML) and relocates PML nuclear bodies to the cytoplasm.
J Virol. 1998 Jan;72(1):758-66
PMID: 9420283
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Transcriptional repression by the promyelocytic leukemia protein, PML.
Exp Cell Res. 1997 Dec 15;237(2):371-82
PMID: 9434633
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The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein.
Mol Cell Biol. 1998 Feb;18(2):1084-93
PMID: 9448006
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Role of PML in cell growth and the retinoic acid pathway.
Science. 1998 Mar 6;279(5356):1547-51
PMID: 9488655
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Two RING finger proteins, the oncoprotein PML and the arenavirus Z protein, colocalize with the nuclear fraction of the ribosomal P proteins.
J Virol. 1998 May;72(5):3819-26
PMID: 9557665
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The mRNA 5' cap-binding protein eIF4E and control of cell growth.
Curr Opin Cell Biol. 1998 Apr;10(2):268-75
PMID: 9561852
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Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4991-6
PMID: 9560216
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Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis.
Oncogene. 1998 Apr 9;16(14):1839-49
PMID: 9583681
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SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements.
Nucleic Acids Res. 1998 Aug 1;26(15):3542-9
PMID: 9671816
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Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies.
Am J Hum Genet. 1998 Aug;63(2):297-304
PMID: 9683622
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Demonstration of a RNA-dependent nuclear interaction between the promyelocytic leukaemia protein and glyceraldehyde-3-phosphate dehydrogenase.
Biochem J. 1998 Nov 1;335 ( Pt 3):691-6
PMID: 9794812
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PML induces a novel caspase-independent death process.
Nat Genet. 1998 Nov;20(3):259-65
PMID: 9806544
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PML is essential for multiple apoptotic pathways.
Nat Genet. 1998 Nov;20(3):266-72
PMID: 9806545
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SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation.
J Cell Sci. 1999 Feb;112 ( Pt 3):381-93
PMID: 9885291
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Evidence for proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro.
Hum Mol Genet. 1999 Apr;8(4):673-82
PMID: 10072437
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The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.
J Mol Biol. 2001 Sep 28;312(4):609-23
PMID: 11575918
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PML protein isoforms and the RBCC/TRIM motif.
Oncogene. 2001 Oct 29;20(49):7223-33
PMID: 11704850
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DNA viruses and viral proteins that interact with PML nuclear bodies.
Oncogene. 2001 Oct 29;20(49):7266-73
PMID: 11704855
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Role and fate of PML nuclear bodies in response to interferon and viral infections.
Oncogene. 2001 Oct 29;20(49):7274-86
PMID: 11704856
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Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes.
Oncogene. 2001 Oct 29;20(49):7287-91
PMID: 11704857
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PML bodies associate specifically with the MHC gene cluster in interphase nuclei.
J Cell Sci. 2001 Oct;114(Pt 20):3705-16
PMID: 11707522
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Self-assembly properties of a model RING domain.
Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):667-72
PMID: 11792829
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Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus.
Nat Cell Biol. 2002 Feb;4(2):106-10
PMID: 11753375
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The emerging roles of translation factor eIF4E in the nucleus.
Differentiation. 2002 Mar;70(1):10-22
PMID: 11963652
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Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E-dependent mRNA transport of cyclin D1 in a PML-dependent manner.
Mol Cell Biol. 2002 Sep;22(17):6183-98
PMID: 12167712
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The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability.
BMC Cell Biol. 2001;2:11
PMID: 11472631
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Construction of macromolecular assemblages in eukaryotic processes and their role in human disease: linking RINGs together.
Curr Protein Pept Sci. 2000 Jul;1(1):49-73
PMID: 12369920