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PMID: 12101120 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning.

Genes & development ·Vol. 16 ·No. 13 ·2002-07-01 ·Pages 1610-5

Hamann T, Benkova E, Bäurle I, Kientz M, Jürgens G

Abstract

Developmental responses to the plant hormone auxin are thought to be mediated by interacting pairs from two protein families: short-lived inhibitory IAA proteins and ARF transcription factors binding to auxin-response elements. monopteros mutants lacking activating ARF5 and the auxin-insensitive mutant bodenlos fail to initiate the root meristem during early embryogenesis. Here we show that the bodenlos phenotype results from an amino-acid exchange in the conserved degradation domain of IAA12. BODENLOS and MONOPTEROS interact in the yeast two-hybrid assay and the two genes are coexpressed in early embryogenesis, suggesting that BODENLOS inhibits MONOPTEROS action in root meristem initiation.

MeSH Terms
Arabidopsis/embryology,genetics Arabidopsis Proteins Base Sequence DNA Primers DNA-Binding Proteins Gene Expression Regulation Genes, Plant Phenotype Promoter Regions, Genetic Seeds/growth & development Transcription Factors/physiology
Chemicals
Arabidopsis Proteins DNA Primers DNA-Binding Proteins MONOPTEROS protein, Arabidopsis Transcription Factors
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Hamann Thorsten
ZMBP, Entwicklungsgenetik, Universität Tübingen, D-72076 Tübingen, Federal Republic of Germany.
Benkova Eva
Bäurle Isabel
Kientz Marika
Jürgens Gerd
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Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
DOI
10.1101/gad.229402
Published
2002-07-01
Pages
1610-5
Language
English
Region
United States
NLM ID
8711660
PMCID
PMC186366
Subset
IM
External Links
PubMed source DOI: 10.1101/gad.229402 PMC Full Text View journal details
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