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PMID: 12094235 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

The phosphatidylinositol 3-Kinase AKT pathway in human cancer.

Nature reviews. Cancer ·Vol. 2 ·No. 7 ·2002-07-00 ·Pages 489-501

Vivanco I, Sawyers CL

Abstract

暂无摘要

MeSH Terms

Animals Cell Division Disease Models, Animal Gene Deletion Humans Lipids Mice Models, Biological Neoplasms/enzymology Phenotype Phosphatidylinositol 3-Kinases/metabolism,physiology Phosphatidylinositol Phosphates/physiology Protein Biosynthesis Protein Serine-Threonine Kinases Proto-Oncogene Proteins/metabolism Proto-Oncogene Proteins c-akt Signal Transduction

Chemicals

Lipids Phosphatidylinositol Phosphates Proto-Oncogene Proteins phosphatidylinositol 3,4,5-triphosphate AKT1 protein, human Protein Serine-Threonine Kinases Proto-Oncogene Proteins c-akt

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Vivanco Igor

Department of Medicine and Molecular Biology Institute, UCLA School of Medicine, 11-935 Factor Building, 10833 LeConte Avenue, Los Angeles, California 90095, USA.

Sawyers Charles L

Article Info

Journal

Nature reviews. Cancer

Abbr.

Nat Rev Cancer

ISSN

1474-175X

DOI

10.1038/nrc839

Published

2002-07-00

Pages

489-501

Language

English

Region

England

NLM ID

101124168

Subset

External Links

PubMed source DOI: 10.1038/nrc839 View journal details

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer.

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