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PMID: 12057681 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Microbial transformation of alkaloids.

Current opinion in microbiology ·Vol. 5 ·No. 3 ·2002-06-00 ·Pages 274-81

Rathbone DA, Bruce NC

Abstract

Alkaloids continue to provide mankind with a plethora of medicines, poisons and potions. Because many valuable drugs are derived from such natural compounds, there is much interest in their transformation to provide new compounds or intermediates for the synthesis of new or improved drugs. This review aims to provide a survey of alkaloid transformations, and concerns microbial transformations and microbially expressed recombinant plant enzymes and their biotechnological applications.

MeSH Terms
Alkaloids/chemistry,metabolism Bacteria/metabolism Drug Design
Chemicals
Alkaloids
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Rathbone Deborah A
Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK.
Bruce Neil C
Article Info
Journal
Current opinion in microbiology
Abbr.
Curr Opin Microbiol
ISSN
1369-5274
Published
2002-06-00
Pages
274-81
Language
English
Region
England
NLM ID
9815056
Subset
IM
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