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PMID: 12033404 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Infectious scrapie agent is apparently not as small as recent claims suggest.

Bioscience reports ·Vol. 3 ·No. 6 ·1983-06-00 ·Pages 563-8

Diringer H, Kimberlin RH

Abstract

A potentially important claim that the minimum size of infectious scrapie agent is 50,000 Mr or less has been investigated. Our results suggest that the agent is larger and that the original experiment was misinterpreted.

MeSH Terms
Animals Brain Chemistry Centrifugation, Density Gradient/methods,veterinary Chromatography, High Pressure Liquid/methods,veterinary Cricetinae Molecular Weight PrPSc Proteins/chemistry
Chemicals
PrPSc Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Diringer H
Robert Koch-Institut des Bundesgesundheitsamtes, Berlin, Germany.
Kimberlin R H
Article Info
Journal
Bioscience reports
Abbr.
Biosci Rep
ISSN
0144-8463
DOI
10.1007/BF01120701
Published
1983-06-00
Pages
563-8
Language
English
Region
England
NLM ID
8102797
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01120701 View journal details
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