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PMID: 1202035 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Initiation of 3T3 fibroblast cell division by epidermal growth factor.

Journal of cellular physiology ·Vol. 86 Suppl 2 ·No. 3 Pt 2 ·1975-12-00 ·Pages 593-8

Rose SP, Pruss RM, Herschman HR

Abstract

Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.

MeSH Terms

Blood Cell Count Cell Division/drug effects Cell Line Cell Survival Culture Media Dose-Response Relationship, Drug Growth Substances/isolation & purification,pharmacology Thymidine/metabolism

Chemicals

Culture Media Growth Substances Thymidine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Rose S P

Pruss R M

Herschman H R

Article Info

Journal

Journal of cellular physiology

Abbr.

J Cell Physiol

ISSN

0021-9541

DOI

10.1002/jcp.1040860504

Published

1975-12-00

Pages

593-8

Language

English

Region

United States

NLM ID

0050222

Subset

External Links

PubMed source DOI: 10.1002/jcp.1040860504 View journal details

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Initiation of 3T3 fibroblast cell division by epidermal growth factor.

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