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PMID: 11994741 Published · ppublish English Historical Article Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Matrix metalloproteinases: a tail of a frog that became a prince.

Nature reviews. Molecular cell biology ·Vol. 3 ·No. 3 ·2002-03-00 ·Pages 207-14

Brinckerhoff CE, Matrisian LM

Abstract

It is 40 years since the first member of what came to be known as the matrix metalloproteinase (MMP) family was described. Structural, molecular and biochemical approaches have subsequently contributed to piecing together the puzzle of how MMPs work, and how they contribute to various disease processes.

MeSH Terms
Animals Cloning, Molecular Gene Expression Regulation, Enzymologic History, 20th Century Humans Matrix Metalloproteinases/chemistry,genetics,history,physiology Models, Biological Models, Molecular Protease Inhibitors/therapeutic use
Chemicals
Protease Inhibitors Matrix Metalloproteinases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Brinckerhoff Constance E
Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
Matrisian Lynn M
Article Info
Journal
Nature reviews. Molecular cell biology
Abbr.
Nat Rev Mol Cell Biol
ISSN
1471-0072
Published
2002-03-00
Pages
207-14
Language
English
Region
England
NLM ID
100962782
Subset
IM
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