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PMID: 11994399 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.

The Journal of clinical investigation ·Vol. 109 ·No. 9 ·2002-05-00 ·Pages 1125-31

Horton JD, Goldstein JL, Brown MS

Abstract

暂无摘要

MeSH Terms
Animals Biological Transport/physiology CCAAT-Enhancer-Binding Proteins/genetics,metabolism Cholesterol/biosynthesis DNA-Binding Proteins/genetics,metabolism Fatty Acids/biosynthesis Gene Expression Regulation Glucagon/metabolism Humans Insulin/metabolism Liver/metabolism Mice Mice, Knockout Models, Biological Protein Isoforms Sterol Regulatory Element Binding Protein 1 Transcription Factors/metabolism
Chemicals
CCAAT-Enhancer-Binding Proteins DNA-Binding Proteins Fatty Acids Insulin Protein Isoforms SREBF1 protein, human Srebf1 protein, mouse Sterol Regulatory Element Binding Protein 1 Transcription Factors Glucagon Cholesterol
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Horton Jay D
Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9046, USA. jay.horton@utsouthwestern.edu
Goldstein Joseph L
Brown Michael S
References (47)
47 references, click to expand
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Article Info
Journal
The Journal of clinical investigation
Abbr.
J Clin Invest
ISSN
0021-9738
DOI
10.1172/JCI15593
Email
jay.horton@utsouthwestern.edu
Published
2002-05-00
Pages
1125-31
Language
English
Region
United States
NLM ID
7802877
PMCID
PMC150968
Subset
IM
Grants
NHLBI NIH HHS · P01 HL020948 · United States
NHLBI NIH HHS · HL-20948 · United States
External Links
PubMed source DOI: 10.1172/JCI15593 PMC Full Text View journal details
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