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PMID: 11972952 Published · ppublish English Journal Article Review

Stereotypy in neocortical microcircuits.

Trends in neurosciences ·Vol. 25 ·No. 5 ·2002-05-00 ·Pages 227-30

Silberberg G, Gupta A, Markram H

Abstract

A central debate regarding neocortical function concerns the degree to which the underlying microcircuitry is stereotypically organized. Stereotypy reflects invariance in structure and function, as a result of common genetic templates and environmental conditions, whereas uniqueness can be caused by genetic variations, differences in environmental conditions as well as random processes. Stereotypy is an appealing concept because it provides strong support for determinism in the formation of neuronal microcircuits and in the relationship between their specific structure and function.

MeSH Terms
Animals Humans Neocortex/anatomy & histology,physiology Nerve Net/anatomy & histology,physiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Silberberg Gilad
Department of Neurobiology, The Weizmann Institute of Science, 76100, Rehovot, Israel.
Gupta Anirudh
Markram Henry
Article Info
Journal
Trends in neurosciences
Abbr.
Trends Neurosci
ISSN
0166-2236
Published
2002-05-00
Pages
227-30
Language
English
Region
England
NLM ID
7808616
Subset
IM
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