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PMID: 11971778 Published · ppublish English Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Invasive group a streptococcal infections, Israel.

Emerging infectious diseases ·Vol. 8 ·No. 4 ·2002-04-00 ·Pages 421-6

Moses AE, Goldberg S, Korenman Z, Ravins M, Hanski E, Shapiro M

Abstract

We conducted a prospective, nationwide, population-based study of invasive group A streptococcal infections in Israel. We identified 409 patients (median age 27 years; range <1-92), for an annual incidence of 3.7/100,000 (11/100,000 in Jerusalem). The mortality rate was 5%. Bacteremia occurred in 125 cases (31%). The most common illnesses were soft-tissue infection (63%) and primary bacteremia (14%). Thirty percent of patients had no identifiable risk factors for infection. Eighty-seven percent of pharyngeal carriers had the same serotype as the index patient. M types included M3 (25%), M28 (10%), and M-nontypable (33%). A marked paucity of M1 serotype (1.2%) was detected. The results highlighted concentrated pockets of invasive disease in the Jewish orthodox community (annual incidence 16/100,000).

MeSH Terms
Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Cohort Studies Humans Incidence Israel/epidemiology Jews Middle Aged Prospective Studies Serotyping Streptococcal Infections/epidemiology,microbiology,mortality Streptococcus/classification,genetics,isolation & purification,pathogenicity
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Moses Allon E
Hadassah University Medical Center, Jerusalem, Isreal. MOSESA@MD2.HUJI.AC.IL
Goldberg Sara
Korenman Zinaida
Ravins Miriam
Hanski Emanuel
Shapiro Mervyn
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Article Info
Journal
Emerging infectious diseases
Abbr.
Emerg Infect Dis
ISSN
1080-6040
DOI
10.3201/eid0804.010278
Email
mosesa@md2.huji.ac.il
Published
2002-04-00
Pages
421-6
Language
English
Region
United States
NLM ID
9508155
PMCID
PMC2730245
Subset
IM
External Links
PubMed source DOI: 10.3201/eid0804.010278 PMC Full Text View journal details
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