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PMID: 1192310 Published · ppublish English Journal Article

Analysis of a measles epidemic; possible role of vaccine failures.

Canadian Medical Association journal ·Vol. 113 ·No. 10 ·1975-11-22 ·Pages 941-4

Rawls WE, Rawls ML, Chernesky MA

Abstract

A measles epidemic occurred in the Greensville (Ont.) Unit schools during January and February 1975. There were 47 cases of measles in 403 students: 26 (55%) of the children had a history of being vaccinated and 18 (38%) had not been vaccinated. Among children known to have been vaccinated at less than 1 year of age 7 of 13 contracted measles, while among the 48 children who had not been vaccinated 18 contracted measles. The attack rate among vaccinees increased with increasing time since vaccination. The observations of this study as well as those of similar studies suggest that vaccine failures contributed to the genesis of the epidemic. It is recommended that all children initially vaccinated at less than 1 year of age should be revaccinated with live attenuated measles virus vaccine.

MeSH Terms
Age Factors Child Child, Preschool Disease Outbreaks/epidemiology Female Humans Immunization, Secondary Male Measles/epidemiology,prevention & control Measles Vaccine Ontario Time Factors Vaccines, Attenuated
Chemicals
Measles Vaccine Vaccines, Attenuated
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Rawls W E
Rawls M L
Chernesky M A
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26 references, click to expand
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Article Info
Journal
Canadian Medical Association journal
Abbr.
Can Med Assoc J
ISSN
0008-4409
Published
1975-11-22
Pages
941-4
Language
English
Region
Canada
NLM ID
0414110
PMCID
PMC1956577
Subset
IM
External Links
PubMed source PMC Full Text
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