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PMID: 11889305 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Discriminative power on mortality of a modified Sequential Organ Failure Assessment score for complete automatic computation in an operative intensive care unit.

Critical care medicine ·Vol. 30 ·No. 2 ·2002-02-00 ·Pages 338-42

Junger A, Engel J, Benson M, Böttger S, Grabow C, Hartmann B, Michel A, Röhrig R, Marquardt K, Hempelmann G

Abstract

To evaluate the discriminative power on mortality of a modified Sequential Organ Failure Assessment (SOFA) score and derived measures (maximum SOFA, total maximum SOFA, and delta SOFA) for complete automatic computation in an operative intensive care unit (ICU). Retrospective study. Operative ICU of the Department of Anesthesiology and Intensive Care Medicine. Patients admitted to the ICU from April 1, 1999, to March 31, 2000 (n = 524). Data from patients under the age of 18 yrs and patients who stayed <24 hrs were excluded. In the case of patient readmittance, only data from the patient's last stay was included in the study. None. The main outcome measure was survival status at ICU discharge. Based on Structured Query Language (SQL) scripts, a modified SOFA score for all patients who stayed in the ICU in 1 yr was calculated for each day in the ICU. Only routine data were used, which were supplied by the patient data management system. Score evaluation was modified in registering unavailable data as being not pathologic and in using a surrogate of the Glasgow Coma Scale. During the first 24 hrs, 459 survivors had an average SOFA score of 4.5 +/- 2.1, whereas the 65 deceased patients averaged 7.6 +/- 2.9 points. The area under the receiver operating characteristic (ROC) curve was 0.799 and significantly >0.5 (p <.01). A confidence interval (CI) of 95% covers the area (0.739-0.858). The maximum SOFA presented an area under the ROC of 0.922 (CI: 0.879-0.966), the total maximum SOFA of 0.921 (CI: 0.882-0.960), and the delta SOFA of 0.828 (CI: 0.763-0.893). Despite a number of differences between completely automated data sampling of SOFA score values and manual evaluation, the technique used in this study seems to be suitable for prognosis of the mortality rate during a patient's stay at an operative ICU.

MeSH Terms
Adult Aged Aged, 80 and over Automation Cost-Benefit Analysis Female Germany/epidemiology Hospital Mortality Humans Intensive Care Units/economics,statistics & numerical data Logistic Models Male Middle Aged Multiple Organ Failure/diagnosis,mortality Retrospective Studies Sensitivity and Specificity Severity of Illness Index Statistics, Nonparametric Survival Rate
Authors & Affiliations
10 authors, click to expand affiliations / ORCID
Junger Axel
Department of Anesthesiology and Intensive Care Medicine, University Hospital Giessen, Giessen, Germany.
Engel Jörg
Benson Matthias
Böttger Sebastian
Grabow Caroline
Hartmann Bernd
Michel Achim
Röhrig Rainer
Marquardt Kurt
Hempelmann Gunter
Article Info
Journal
Critical care medicine
Abbr.
Crit Care Med
ISSN
0090-3493
Published
2002-02-00
Pages
338-42
Language
English
Region
United States
NLM ID
0355501
Subset
IM
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