125I-Labelled tetanus toxin as a neuronal marker in tissue cultures derived from embryonic CNS.

Naunyn-Schmiedeberg's archives of pharmacology ·Vol. 290 ·No. 2-3 ·1975-00-00 ·Pages 329-33

Dimpfel W, Neale JH, Habermann E

Abstract

Primary cultures derived from embryonic mouse brain and spinal cord were exposed to 125I-labelled tetanus toxin and subjected to autoradiography. Cells with neuronal, but not glial, morphology selectively accumulated the toxin. The distribution of the grains over these cells and their processes was not uniform, discrete processes showing heavier labelling.

MeSH Terms

Animals Brain/embryology,metabolism Culture Techniques Mice Motor Neurons/metabolism Neuroglia/metabolism Neurons/metabolism Spinal Cord/embryology,metabolism Tetanus Toxin/metabolism

Chemicals

Tetanus Toxin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Dimpfel W

Neale J H

Habermann E

Article Info

Journal

Naunyn-Schmiedeberg's archives of pharmacology

Abbr.

Naunyn Schmiedebergs Arch Pharmacol

ISSN

0028-1298

DOI

10.1007/BF00510562

Published

1975-00-00

Pages

329-33

Language

English

Region

Germany

NLM ID

0326264

Subset

External Links

PubMed source DOI: 10.1007/BF00510562 View journal details

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125I-Labelled tetanus toxin as a neuronal marker in tissue cultures derived from embryonic CNS.

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